[PDF] Plant Extracts as Skin Care and Therapeutic Agents | Semantic Scholar (2024)

The availability of E. angustifolium in the market as a raw material for cosmetics offers opportunities for formulators to create innovative products with skin-conditioning and anti-inflammatory properties.

The individual roles of plant extracts, antioxidants, peptides, and probiotics in personal care products are explored, while emphasizing their synergistic effects when combined to highlight the potential for developing innovative skincare formulations that not only address specific skin concerns but also contribute to overall skin health.

The red fruit seed extract obtained using methanol demonstrated potential anticancer effects against Ca9-22 oral carcinoma cells by inhibiting cell survival, migration, and proliferation as well as inducing apoptosis, underscore the potential of S. betaceum fruit extracts, especially from red fruit seeds, as promising agents for anti-skin aging and anticancer applications, meriting further exploration for therapeutic uses.

The results revealed that all three dry extracts effectively stimulate skin cell migration, highlighting a potential anti-inflammatory effect by increasing the cell migration rate in conditions of induced inflammation associated with oxidative stress.

This comprehensive review intends to present the most significant and recent studies regarding the plethora of AV’s biological activities and an in-depth analysis exploring the component/s responsible for them.

AESFEO has beneficial effects on keratinocyte activities related to skin wound healing and melanocyte activities related to inhibition of skin pigmentation, suggesting it may serve as a useful natural substance for developing agents that facilitate skin wound healing and inhibit melanogenesis.

The mucilage-containing aqueous extract of ALBU was shown for the first time to induce the highest fibroblast migration after 24 h, not evident in TELE, and functional constituents contained within the absolute acetone- and isopropanol-containing polyphenol pools from ALBU induced significantly higher migration compared to TELE.

The extract demonstrated anticancer potential against Ca9-22 oral carcinoma cells by inhibiting cell survival, migration, and proliferation and inducing apoptosis, and underscore the potential of P. edulis (Tainung No. 1) rind as a promising candidate for anti-skin aging, antibacterial, and anticancer applications, meriting further therapeutic investigation.

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Of numerous botanicals, the phenolic acids and flavonoids appear effective against UVR-induced damage; however the evidence-based studies for their anti-aging effects are still needed.

It has been shown that the highest antioxidant capacity can be observed for the extract of herb of Aegopodium podagraria L. extract, which inhibits the activity of collagenase and elastase enzymes by over 70% in the concentration of 5% positively affecting the condition of skin cells.

Although plant EOs are considered promising natural alternatives for many chemical drugs, they still need more specific research for wide application especially in food and pharmaceutical industries.

The modern medicine still needs the help of the alternative and complementary medicine, which is most often based on phytotherapy, and the identification and characterization of plant extracts and their major bioactive phytochemicals are highly valuable, especially if they are proved to be more efficient and less toxic than that of conventional chemical formulations.

Evaluation of photoprotective activity of aqueous extracts of eleven medicinal plants in Sri Lanka suggest that the presence of secondary metabolites with antioxidant property could be responsible for the high UV absorbance.

E. characias nanoformulation was also cytocompatible and improved the extract’s activity in the cells, suggesting a potential skin application for antimelanogenic treatments and confirming the key role of nanotechnological approaches to maximize plant extract's potentialities.

The studied extracts showed high photoprotection efficacy and antigenotoxicity against UVB radiation, but only the P. latifolia Extract appeared to be safer for human fibroblast cells and the R. centifolia extract was shown to be moderately cytotoxic and genotoxic at the highest assayed concentrations.

In vitro penetration studies showed that the active ingredients contained in E. angustifolium penetrate through human skin and accumulate in it, and can be considered as an interesting alternative for dermatologic and cosmetic preparations.

An updated review of the available literature related to the most recent advances in the application of EOs and EOCs in the manufacturing of cosmetic products is presented and it is expected that the information can be exploited by formulators in the design and optimization of cosmetic formulations containing botanical extracts.

The main aims of this research were to promote its consumption in the Comoros Islands as potential health-promoting food and evaluate it as a source of bioactive molecules for the food industry thanks to its antioxidant and antibacterial properties.

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